Santa Elisabetta (Sicilian: Sabbetta) is a small town (municipality) in the Province of Agrigento in the Italian region Sicily, located about 80 kilometres (50 mi) south of Palermo and about 13 kilometres (8 mi) north of Agrigento. As of 31 December 2004, it had a population of 2,906 and an area of 16.2 square kilometres (6.3 sq mi).

Santa Elisabetta borders the following municipalities: Aragona, Joppolo Giancaxio, Raffadali, Sant'Angelo Muxaro.